| Miércoles 20/10/20 | |||||
| Fernando de la Mora | 2 | 0 | General Díaz | Fin | |
| Jueves 21/10/21 | |||||
| Trinidense | 2 | 1 | Guaraní (T) | Fin | |
| Viernes 22/10/22 | |||||
| 3 de Febrero CDE | 1 | 4 | Gral. Caballero JLM | Fin | |
| Lunes 25/10/25 | |||||
| Fulgencio Yegros | D. Capiatá | 09:30hs | |||
| Atyra FC | Dep. Santaní | 09:30hs | |||
| Martes 26/10/26 | |||||
| Sp. Ameliano | Sp. Iteño | 15:30hs | |||
| Tacuary | Rubio Ñu | 15:30hs | |||
| 2 de Mayo | San Lorenzo | 15:30hs | |||
| Resistencia SC | Independiente CG | 15:30hs | |||