| Jugador | Equipo | Goles | GJ | GC. | TL | TP |
| Ola Kamara | DC United | 17 | 7 | 2 | 0 | 8 |
| Daniel Salloi | Sporting KC | 16 | 16 | 0 | 0 | 0 |
| Raúl Ruidíaz | Seattle | 16 | 12 | 0 | 1 | 3 |
| Gustavo Bou | New England | 15 | 14 | 0 | 0 | 1 |
| Damir Kreilach | Real SL | 14 | 7 | 7 | 0 | 0 |
| Adam Buksa | New England | 14 | 9 | 5 | 0 | 0 |
| Hany Mukhtar | Nashville SC | 14 | 12 | 0 | 1 | 1 |
| Ricardo Pepi | FC Dallas | 13 | 11 | 2 | 0 | 0 |
| Javier Hernández | LA Galaxy | 13 | 12 | 1 | 0 | 0 |
| Valentín Castellanos | NYCFC | 13 | 7 | 3 | 0 | 3 |