| Jugador | Equipo | Goles | GJ | GC. | TL | TP |
| Christian Benteke | DC United | 19 | 8 | 8 | 0 | 3 |
| Luis Suárez | Miami | 17 | 16 | 1 | 0 | 0 |
| Cristian Arango | Real SL | 17 | 8 | 7 | 0 | 2 |
| Denis Bouanga | LAFC | 17 | 10 | 0 | 0 | 7 |
| Mateusz Bogusz | LAFC | 14 | 10 | 2 | 2 | 0 |
| Dejan Joveljic | LA Galaxy | 14 | 12 | 1 | 0 | 1 |
| Lionel Messi | Miami | 14 | 12 | 1 | 0 | 1 |
| Petar Musa | FC Dallas | 14 | 12 | 1 | 0 | 1 |
| Daniel Gazdag | Philadelphia | 14 | 7 | 3 | 0 | 4 |
| Rafael Navarro | Rapids | 14 | 8 | 2 | 0 | 4 |