| Jugador | Equipo | Goles | GJ | GC. | TL | TP |
| Cristiano Ronaldo | Juventus | 29 | 16 | 7 | 0 | 6 |
| Romelu Lukaku | Inter | 24 | 17 | 1 | 0 | 6 |
| Luis Muriel | Atalanta | 22 | 20 | 0 | 0 | 2 |
| Dusan Vlahovic | Fiorentina | 21 | 13 | 2 | 0 | 6 |
| Ciro Immobile | Lazio | 20 | 13 | 3 | 0 | 4 |
| Simeon Nwankwo | Crotone | 20 | 11 | 1 | 0 | 8 |
| Lorenzo Insigne | Napoli | 19 | 11 | 0 | 1 | 7 |
| Lautaro Martínez | Inter | 17 | 11 | 4 | 0 | 2 |
| Domenico Berardi | Sassuolo | 17 | 9 | 0 | 1 | 7 |
| João Pedro | Cagliari | 16 | 10 | 2 | 0 | 4 |