| Jugador | Equipo | Goles | GJ | GC. | TL | TP |
| Lautaro Martínez | Inter | 23 | 19 | 2 | 0 | 2 |
| Dusan Vlahovic | Juventus | 16 | 10 | 2 | 2 | 2 |
| Victor Osimhen | Napoli | 13 | 7 | 4 | 0 | 2 |
| Albert Gudmundsson | Genoa | 13 | 8 | 0 | 1 | 4 |
| Olivier Giroud | Milan | 13 | 3 | 6 | 0 | 4 |
| Duván Zapata | Torino | 12 | 5 | 7 | 0 | 0 |
| Marcus Thuram | Inter | 12 | 11 | 1 | 0 | 0 |
| Paulo Dybala | Roma | 12 | 5 | 0 | 1 | 6 |
| Romelu Lukaku | Roma | 11 | 9 | 2 | 0 | 0 |
| Teun Koopmeiners | Atalanta | 11 | 6 | 2 | 1 | 2 |