| Jugador | Equipo | Goles | GJ | GC. | TL | TP |
| Victor Osimhen | Napoli | 23 | 15 | 7 | 0 | 1 |
| Lautaro Martínez | Inter | 21 | 18 | 2 | 0 | 1 |
| Boulaye Dia | Salernitana | 16 | 15 | 0 | 0 | 1 |
| Rafael Leão | Milan | 13 | 12 | 1 | 0 | 0 |
| Ademola Lookman | Atalanta | 13 | 9 | 1 | 0 | 3 |
| Mbala Nzola | Spezia | 13 | 9 | 1 | 0 | 3 |
| Antonio Sanabria | Torino | 12 | 9 | 2 | 0 | 1 |
| Khvicha Kvaratskhelia | Napoli | 12 | 10 | 0 | 0 | 2 |
| Ciro Immobile | Lazio | 12 | 7 | 1 | 0 | 4 |
| Olivier Giroud | Milan | 11 | 5 | 4 | 0 | 2 |