| Viernes 21/09/21 | |||||
| Bucaramanga | 2 | 1 | Jaguares | Fin | |
| Chicó | 1 | 1 | Patriotas FC | Fin | |
| Sábado 22/09/22 | |||||
| Junior | 3 | 1 | La Equidad | Fin | |
| Rionegro | 2 | 1 | Leones FC | Fin | |
| Medellín | 2 | 2 | Santa Fe | Fin | |
| Millonarios | 2 | 2 | Once Caldas | Fin | |
| Domingo 23/09/23 | |||||
| Dep. Cali | 0 | 1 | Tolima | Fin | |
| Pasto | 2 | 1 | A. Petrolera | Fin | |
| Huila | 1 | 0 | A. Nacional | Fin | |
| Lunes 24/09/24 | |||||
| Envigado | 1 | 1 | América | Fin | |