| Sábado 20/04/20 | |||||
| Pereira | 1 | 2 | Millonarios | Fin | |
| Junior | 1 | 0 | Once Caldas | Fin | |
| Alianza | 2 | 1 | Jaguares | Fin | |
| Domingo 21/04/21 | |||||
| Santa Fe | 1 | 0 | América | Fin | |
| Dep. Cali | 2 | 0 | Envigado | Fin | |
| Indep. Medellín | 2 | 2 | A. Nacional | Fin | |
| Tolima | 2 | 1 | Patriotas FC | Fin | |
| Lunes 22/04/22 | |||||
| Fortaleza FC | 0 | 2 | Bucaramanga | Fin | |
| Chicó | 1 | 2 | Águilas Doradas | Fin | |
| Pasto | 2 | 3 | La Equidad | Fin | |